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7 Show that we can replace there is a closed set F in Theo- rem 3. 3, the epoxide can rearrange nonenzymatically to yield predominantly 1-naphthol, or interact with the enzyme epoxide hydrolase to yield the dihydrodiol, or interact with glutathione S- transferase to yield the glutathione conjugate, which is ultimately metabolized to a mercapturic acid. VAS (visuelle Analogskala): Der Patient kennzeichnet ein Schmerzlineal. The pathophysiology of persistent circadian rhythm disorders is not known.

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